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The North American Antiepileptic Drug Pregnancy Registry reported 16 cases of congenital malformations among the offspring of 149 women with epilepsy who were exposed to valproic acid monotherapy during the first trimester of pregnancy at doses of approximately 1,000 mg per day, for a prevalence rate of 10.7% (95% CI 6.3% to 16.9%). Three of the 149 offspring (2%) had neural tube defects and 6 of the 149 (4%) had less severe malformations.
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Urine and blood tests will show very high levels of glucose.
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Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents.
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The initial bite may or may not be noticed by the victim.
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Serum and urine electrolyte determinations are particularly important when the patient is vomiting profusely or receiving parenteral fluids.
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They may also be called leukemic cells.
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Screening Patients for Bipolar Disorder — A major depressive episode may be the initial presentation of bipolar disorder.
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In 13 week toxicity studies, theophylline was administered to F344 rats and B6C3F1 mice at oral doses of 40-300 mg/kg (approximately 2.0 times the human dose on a mg/m2 basis).
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This method involves giving high doses of chemotherapy and replacing blood -forming cells destroyed by the cancer treatment.